Cooper P J, Murray L, Hooper R, West A
Winnicott Research Unit, Department of Psychiatry, University of Cambridge.
Psychol Med. 1996 May;26(3):627-34. doi: 10.1017/s0033291700035698.
A sample of over 6000 women was recruited in the last trimester of pregnancy and administered a 40-item self-report questionnaire designed to detect the presence of factors that were likely to increase the risk of postpartum depression. The mental state of almost 5000 of these women was determined at around 6 to 8 weeks postpartum. By conducting a series of logistic regressions on two-thirds of this sample the original set of variables was reduced to a predictive index of 17 items with weighted scores calculated for each. This index was then applied to the remaining one-third of the sample as a validating procedure and specificity and sensitivity calculated. The index offers a system for the prediction of postpartum depression that could be of use in both research and clinical practice.
在妊娠晚期招募了6000多名女性样本，并让她们填写一份40项的自我报告问卷，该问卷旨在检测可能增加产后抑郁风险的因素。其中近5000名女性的心理状态在产后6至8周左右进行了测定。通过对该样本三分之二的数据进行一系列逻辑回归分析，原始变量集被缩减为一个由17项组成的预测指数，每项都计算了加权分数。然后将该指数应用于样本的其余三分之一作为验证程序，并计算特异性和敏感性。该指数提供了一个预测产后抑郁的系统，可用于研究和临床实践。
