沙林：神经性毒气袭击受害者管理指南
Sarin: guidelines on the management of victims of a nerve gas attack.
作者信息
Volans A P
机构信息
Department of Accident and Emergency, Royal Hallamshire Hospital, Sheffield.
出版信息
J Accid Emerg Med. 1996 May;13(3):202-6. doi: 10.1136/emj.13.3.202.
Abstract
Sarin is now a weapon of the terrorist. Its acute effects are primarily due to unrestricted cholinergic activity at both muscarinic and nicotinic receptors. Treatment is based on the use of large doses of atropine and pralidoxime which may lead to practical problems of sufficient drug supplies for the average hospital. Ventilation may be necessary and present problems. Victim decontamination involves use of bleach, soap and water. Staff handling casualties need protection with respirators and butyl rubber boots and gloves.
摘要
沙林现在是恐怖分子的一种武器。其急性效应主要是由于毒蕈碱和烟碱受体处不受限制的胆碱能活性。治疗基于使用大剂量的阿托品和氯解磷定，这可能给普通医院带来药物供应充足性的实际问题。可能需要进行通气，且存在相关问题。对受害者进行去污处理需要使用漂白剂、肥皂和水。处理伤亡人员的工作人员需要佩戴呼吸器以及穿着丁基橡胶靴和手套进行防护。
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