利用一种简单的化学传感器在鲶鱼脑中可视化 DCP，一种神经毒剂模拟物。
Visualisation of DCP, a nerve agent mimic, in Catfish brain by a simple chemosensor.
机构信息
Department of Chemistry, Visva-Bharati University, Santiniketan, 731235, India.
Department of Microbiology, University of Calcutta, Kolkata, 700019, India.
出版信息
Sci Rep. 2018 Feb 21;8(1):3402. doi: 10.1038/s41598-018-21780-5.
Abstract
A chemosensor, 3-aminophenol-based rhodamine conjugate (ARC) has been developed for visualisation of diethylchlorophosphate (DCP), mimic of a chemical warfare agent, in Catfish brain. The simple detection of DCP by "turn-on" fluorescence property of the chemosensor makes it unique for easy and rapid in vivo and in vitro detection of DCP with the detection limit of 5.6 nM.
摘要
一种基于 3-氨基酚的罗丹明化学传感器 (ARC) 已被开发用于可视化鲶鱼脑中的二乙基氯膦 (DCP)，DCP 是一种化学战剂的模拟物。该化学传感器具有“开启”荧光性质，可简单检测 DCP，使其具有独特的优势，可用于 DCP 的体内和体外的简便快速检测，检测限为 5.6 nM。
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