Bernadat J P, Faucher J F, Huerre M
Clinique Paofai, Papeete, Tahiti, Polynésie française.
Ann Dermatol Venereol. 1996;123(1):21-3.
Lucio's phenomenon, also called necrotizing erythema, is a rare acute manifestation which sometimes introduces diffuse lepromatous leprosy, almost exclusively in Central American populations.
A 76-year-old polynesian man of chinese ethnic origin had necrotizing erythema for several months before development of Lucio's leprosy. The patient had necrotizing lesions of the lower limbs with large polygonal scars and poor general health status. Diagnosis was based on the discovery of acid-fast bacilli at the pathology examination of skin biopsies. The necrotizing zones appeared as cutaneous vasculitis with angiogenesis of the superficial dermis and presence of Hansen bacilli within the endothelium.
This case of diffuse lepromatous leprosy, the first reported in the South Pacific, emphasizes the polymorphism of leprosy and the importance of recognizing rare clinical forms, especially in the tropics. Anti-Hansen drugs are effective.
卢西奥现象，也称为坏死性红斑，是一种罕见的急性表现，有时会引发弥漫性瘤型麻风，几乎仅见于中美洲人群。
一名76岁的华裔波利尼西亚男子在出现卢西奥麻风之前已有数月的坏死性红斑。患者下肢有坏死性病变，伴有大片多边形瘢痕，全身健康状况较差。诊断基于皮肤活检病理检查中发现抗酸杆菌。坏死区域表现为皮肤血管炎，伴有浅表真皮血管生成，内皮细胞内存在汉森杆菌。
这例弥漫性瘤型麻风病例是南太平洋地区首例报告，强调了麻风的多态性以及认识罕见临床形式的重要性，尤其是在热带地区。抗汉森药物有效。
