Ribaric S, Peterec D, Sketelj J
Institute of Pathophysiology, Medical Faculty, University of Ljubljana, Slovenia.
Comput Methods Programs Biomed. 1996 Mar;49(2):149-56. doi: 10.1016/0169-2607(96)01719-1.
Acetylcholinesterase (AChE) is an enzyme that appears in several molecular forms. Individual AChE molecular forms can be isolated and identified on the basis of their velocity sedimentation profiles. We have improved an existing method for analyzing AChE sedimentation profiles with a computer aided data acquisition and analysis system. The software facilitates measurements of AChE activity of individual molecular forms and comparison among AChE velocity sedimentation profiles. In practice, our program increased precision and reduced the time of AChE velocity sedimentation profile analysis. The software can also be applied to velocity sedimentation analysis of other proteins. We plan to upgrade the program by making it compatible with Microsoft Windows.
乙酰胆碱酯酶（AChE）是一种以多种分子形式出现的酶。可以根据其速度沉降谱分离和鉴定单个AChE分子形式。我们利用计算机辅助数据采集和分析系统改进了一种现有的分析AChE沉降谱的方法。该软件有助于测量单个分子形式的AChE活性，并比较AChE速度沉降谱。在实际应用中，我们的程序提高了精度，减少了AChE速度沉降谱分析的时间。该软件还可应用于其他蛋白质的速度沉降分析。我们计划通过使其与Microsoft Windows兼容来升级该程序。
