Smith K R, Fisher H C, Hook E W
Department of Medicine, University of Alabama at Birmingham, USA.
J Clin Microbiol. 1996 Jun;34(6):1551-2. doi: 10.1128/jcm.34.6.1551-1552.1996.
We compared a direct fluorescent monoclonal antibody (DFA) test with alternative enzymatic and fermentation tests for identifying presumptive gonococcal isolates in a systematic sample from patients attending five sexually transmitted disease clinics in five cities. Fourteen (2.5%) of 556 isolates from three clinics were nonreactive with DFA confirmatory reagent and reactive by both the Quad-Ferm (BioMerieux Vitek Inc.) and the Rapid NH (Innovative Diagnostic Systems, Inc.) tests. The prevalence of DFA-nonreactive Neisseria gonorrhoeae isolates varies geographically and is independent of local methods for the identification of possible gonococci.
我们比较了直接荧光单克隆抗体(DFA)检测与其他酶法和发酵试验,以鉴定来自五个城市五家性传播疾病诊所患者的系统样本中的推定淋病奈瑟菌分离株。来自三家诊所的556株分离株中有14株(2.5%)与DFA确证试剂无反应,但通过Quad-Ferm(生物梅里埃维泰克公司)和Rapid NH(创新诊断系统公司)检测呈阳性。DFA无反应性淋病奈瑟菌分离株的流行率存在地域差异,且与当地鉴定可能的淋病奈瑟菌的方法无关。