Gillespie R R, Hill M A, Kanitz C L
Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907, USA.
Res Vet Sci. 1996 May;60(3):228-33. doi: 10.1016/s0034-5288(96)90044-2.
On three consecutive days, six pigs were exposed for 15 minutes to aerosols of Aujeszky's disease virus. The total estimated dose was 4.5 log 10 TCID50. Within each isolation room, a sentinel pig was placed on a deck two feet away from the infected pig. The breath of the pigs that had inhaled the aerosols was collected on days 3, 7 and 13. The respiratory and other clinical signs of the infected pigs resembled those in field cases of Aujeszky's disease. All the pigs infected with Aujeszky's disease virus seroconverted within seven to 10 days after infection. Among the sentinel pigs, clinical signs were minimal and only three seroconverted.
连续三天,六头猪暴露于伪狂犬病病毒气溶胶中15分钟。估计总剂量为4.5 log₁₀ TCID₅₀。在每个隔离室内,将一头哨兵猪放置在距离感染猪两英尺远的平台上。在第3天、第7天和第13天收集吸入气溶胶的猪的呼吸样本。感染猪的呼吸道及其他临床症状与伪狂犬病的田间病例相似。所有感染伪狂犬病病毒的猪在感染后7至10天内血清转化。在哨兵猪中,临床症状轻微,只有三头发生了血清转化。