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猪的实验性奥耶斯基氏病:病毒的排泄、存活及传播

Experimental Aujeszky's disease in pigs: excretion, survival and transmission of the virus.

作者信息

Donaldson A I, Wardley R C, Martin S, Ferris N P

出版信息

Vet Rec. 1983 Nov 19;113(21):490-4. doi: 10.1136/vr.113.21.490.

DOI:10.1136/vr.113.21.490
PMID:6316624
Abstract

Airborne Aujeszky's disease virus was recovered from looseboxes containing groups of pigs infected with virus strains from England, Northern Ireland and Denmark from days 1 to 7 after infection. Pigs sampled individually excreted most airborne virus on days 2 and 3 after infection. On a 24 hour basis the maximum amount of airborne virus excreted per pig was log10 5.3 TCID50. Subclinical infection was transmitted from a clinically affected group of pigs to a seronegative group held in separate looseboxes when air was drawn through ducting connecting one box with the other. Tissues taken from pigs killed at varying times after infection showed that the main sites of virus replication were in the head and neck region. Aujeszky's disease virus was detected for up to 40 days in a range of tissues taken from pigs at the acute stage of disease and stored at -20 degrees C.

摘要

在感染后第1天至第7天,从装有感染了来自英格兰、北爱尔兰和丹麦病毒株的猪群的猪舍中分离出空气传播的奥耶斯基氏病病毒。个体采样的猪在感染后第2天和第3天排出的空气传播病毒最多。在24小时内,每头猪排出的空气传播病毒的最大量为log10 5.3 TCID50。当空气通过连接一个猪舍与另一个猪舍的管道抽吸时,亚临床感染从一组临床受影响的猪传播到单独猪舍中的血清阴性猪群。对感染后不同时间处死的猪采集的组织进行检测,结果表明病毒复制的主要部位在头部和颈部区域。在疾病急性期采集并储存在-20摄氏度的一系列猪组织中,长达40天可检测到奥耶斯基氏病病毒。

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