Wolk R
Department of Physiology, Institute of Physiological Sciences, Faculty of Medicine, Warsaw, Poland.
Med Hypotheses. 1996 May;46(5):479-81. doi: 10.1016/s0306-9877(96)90029-8.
Sympathetic activity influences the total power of the heart rate variability spectrum. Decreased heart rate variability and increased sympathetic tone have been related to poor prognosis and an increased risk of sudden cardiac death in patients with myocardial infarction, congestive heart failure or hypertension. On the basis of recent experimental data, I propose that these disease states are associated with altered spectral characteristics of the central sympathetic activity generated within rostral ventrolateral medulla neurones, which subsequently leads to decreased heart rate variability and increased systemic sympathetic tone.
交感神经活动影响心率变异性频谱的总功率。心率变异性降低和交感神经张力增加与心肌梗死、充血性心力衰竭或高血压患者的预后不良及心脏性猝死风险增加有关。基于最近的实验数据，我提出这些疾病状态与延髓头端腹外侧神经元产生的中枢交感神经活动的频谱特征改变有关，这随后会导致心率变异性降低和全身交感神经张力增加。
