Wang J S, Toksvig-Larsen S, Müller-Wille P, Franźen H
Department of Orthopedics, Lund University Hospital, Sweden.
J Biomed Mater Res. 1996 Summer;33(2):115-9. doi: 10.1002/(SICI)1097-4636(199622)33:2<115::AID-JBM8>3.0.CO;2-U.
Six vacuum mixing systems, Cemvac, Merck, Mitvac, Optivac, Osteobond, and Stryker, were tested using prechilled Palacos R bone cement to investigate the reduction of porosity compared to mixing at atmospheric pressure. In addition the Optivac, Osteobond, and Stryker were tested using Simplex P bone cement to find out if they were effective in reducing the porosity of a middle viscosity bone cement. All vacuum mixing systems reduced the number of macropores (> 1 mm) and micropores (0.1 mm < voids < 1 mm) and increased the density of both Palacos R and Simplex P. But only the Optivac, Stryker, and Merck systems reduced the area percentage of macropores with more than 50% compared to the control. When using Simplex P bone cement, all three mixing systems tested reduced the numbers and the area percentage of macropores compared to the control. The results show that vacuum mixing is effective in reducing the porosity in both a high viscosity cement such as Palacos R and a middle viscosity cement such as Simplex P. Not all systems tested were effective in reducing the number and size of large voids.
使用预冷的Palacos R骨水泥对六种真空搅拌系统Cemvac、Merck、Mitvac、Optivac、Osteobond和Stryker进行测试，以研究与常压搅拌相比孔隙率的降低情况。此外，使用Simplex P骨水泥对Optivac、Osteobond和Stryker进行测试，以确定它们在降低中粘度骨水泥孔隙率方面是否有效。所有真空搅拌系统都减少了大孔（>1毫米）和微孔（0.1毫米<孔隙<1毫米）的数量，并提高了Palacos R和Simplex P的密度。但与对照组相比，只有Optivac、Stryker和Merck系统减少了50%以上的大孔面积百分比。使用Simplex P骨水泥时，与对照组相比，测试的所有三种搅拌系统都减少了大孔的数量和面积百分比。结果表明，真空搅拌在降低高粘度水泥（如Palacos R）和中粘度水泥（如Simplex P）的孔隙率方面是有效的。并非所有测试系统在减少大孔隙的数量和尺寸方面都有效。
