Müller-Wille P, Wang J S, Lidgren L
Department of Orthopedics, Lund University Hospital, Sweden.
J Biomed Mater Res. 1997 Summer;38(2):135-42. doi: 10.1002/(sici)1097-4636(199722)38:2<135::aid-jbm8>3.0.co;2-r.
We developed a prepacked mixing system for the preparation of bone cement. The system is based on mixing and collection of bone cement under a vacuum and serves as both the storage and mixing device for the cement components, thereby minimizing the exposure of the operating staff to the monomer and the risk for contamination of the cement during preparation. We evaluated the system using Palacos R and Simplex P. The cement produced was compared with cement obtained from a commercially available mixing system. Temperature evolution during curing, handling characteristics, density, and porosity of the cement obtained were analyzed. The results showed that the experimental system produces cement with physical properties (i.e., setting times and temperature, porosity, and density) equal to or better than those obtained with commercially available systems. Reducing the amount of monomer in the experimental system led to a reduction of the curing temperature without compromising the physical properties of the cements.
我们开发了一种用于制备骨水泥的预包装混合系统。该系统基于在真空下对骨水泥进行混合和收集，兼具骨水泥各组分的储存和混合功能，从而最大程度减少操作人员接触单体的机会以及制备过程中骨水泥受污染的风险。我们使用Palacos R和Simplex P对该系统进行了评估。将所制备的骨水泥与从市售混合系统获得的骨水泥进行比较。分析了固化过程中的温度变化、操作特性、所获骨水泥的密度和孔隙率。结果表明，该实验系统所制备的骨水泥的物理性能（即凝固时间、温度、孔隙率和密度）与市售系统相当或更优。在实验系统中减少单体用量可降低固化温度，且不影响骨水泥的物理性能。
