Abinader E G, Sharif D, Sagiv M, Goldhammer E
Heart Institute and CCU, Bnai Zion Medical Center: (Rothschild), Technion, Haifa, Israel.
Eur Heart J. 1996 Mar;17(3):457-61. doi: 10.1093/oxfordjournals.eurheartj.a014880.
Hypertrophy of the left ventricle may be associated with altered left ventricular filling dynamics. To test whether isometric and isotonic training affect left ventricular filling differently at rest and during isometric stress, 38 males, 13 long distance runners, eight weight-lifters, eight hypertensive patients and nine age-matched healthy male controls with a mean age of 30 +/- 7 years, were studied before and after 90 s of 50% maximal handgrip force. Left ventricular Doppler filling parameters were compared in the four groups while they were resting and during isometric stress testing, and the results assessed in relation to left ventricular mass index and wall stress. All subjects had normal resting filling patterns except for hypertensive patients, and peak meridional wall stress was low in both athletic groups at rest. Weight-lifters had a hypertensive response during isometric stress testing, associated with a reduction in peak E velocity and a marked increase in peak A velocity, resembling the filling pattern in hypertensive subjects. In runners the filling pattern remained normal. Thus, while the resting left ventricular pattern was normal in all athletes, isometric stress testing was associated with a hypertensive filling pattern only in weight-lifters compared to normal filling in runners.
左心室肥厚可能与左心室充盈动力学改变有关。为了测试等长训练和等张训练在静息状态和等长应激期间对左心室充盈的影响是否不同，我们对38名男性进行了研究，其中包括13名长跑运动员、8名举重运动员、8名高血压患者和9名年龄匹配的健康男性对照者，平均年龄为30±7岁。在50%最大握力持续90秒前后对他们进行了研究。比较了四组在静息状态和等长应激测试期间的左心室多普勒充盈参数，并根据左心室质量指数和壁应力评估结果。除高血压患者外，所有受试者静息时的充盈模式均正常，两个运动组静息时的最大经线壁应力均较低。举重运动员在等长应激测试期间出现高血压反应，伴有E峰速度降低和A峰速度显著增加，类似于高血压患者的充盈模式。跑步运动员的充盈模式保持正常。因此，虽然所有运动员静息时的左心室模式正常，但与跑步运动员的正常充盈相比，等长应激测试仅在举重运动员中与高血压充盈模式相关。
