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Sequence of the nucleocapsid protein gene of subgroup A and B avian pneumoviruses.

作者信息

Li J, Ling R, Randhawa J S, Shaw K, Davis P J, Juhasz K, Pringle C R, Easton A J, Cavanagh D

机构信息

Institute for Animal Health, Compton Laboratory, Newbury, UK.

出版信息

Virus Res. 1996 Apr;41(2):185-91. doi: 10.1016/0168-1702(96)01288-9.

DOI:10.1016/0168-1702(96)01288-9
PMID:8738178
Abstract

The nucleocapsid protein (N) gene of two subgroup A and one subgroup B strains of avian pneumovirus has been cloned and sequenced. The gene of all three isolates comprised 1197 nucleotides (nt), which formed a single major open reading frame, potentially encoding a protein of 391 amino acid residues. The N gene of the two subgroup A isolates differed by only 1 nt but differed by 282 (24%) nt and 35 (11%) amino acids from the B isolate. The predicted protein was identical in length to that of human, bovine and ovine respiratory syncytial viruses, the amino acid identity being approximately 41% overall but with some regions of identity > 90%.

摘要

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