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以视觉障碍为首发症状的原发性脊髓软膜胶质瘤病:病例报告

Primary spinal leptomeningeal gliomatosis presenting visual disturbance as the initial symptom: case report.

作者信息

Kobayashi M, Hara K, Nakatsukasa M, Murase I, Toya S

机构信息

Department of Neurosurgery, Keio University, Tokyo, Japan.

出版信息

Acta Neurochir (Wien). 1996;138(4):480-1. doi: 10.1007/BF01420313.

Abstract

We report a case of diffuse leptomeningeal gliomatosis which spread from the cervical to the sacral spine. A 60-year-old man was admitted with visual disturbance due to papilledema. Magnetic resonance imaging revealed holocord leptomeningeal gliomatosis without a definite intraparenchymal lesion, and the patient's neurological examination was unremarkable except for papilledema. Intracranial hypertension secondary to spinal tumor is well known but unusual, and the mechanism is still unclear. In our case, an elevated protein concentration of cerebrospinal fluid is suggested as the cause of intracranial hypertension.

摘要

我们报告一例弥漫性软脑膜胶质瘤病,其从颈椎扩散至骶椎。一名60岁男性因视乳头水肿导致视力障碍入院。磁共振成像显示全脊髓软脑膜胶质瘤病,无明确的脑实质内病变,除视乳头水肿外,患者的神经系统检查无异常。脊髓肿瘤继发颅内高压虽为人熟知但并不常见,其机制仍不清楚。在我们的病例中,脑脊液蛋白浓度升高被认为是颅内高压的原因。

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