Heye N, Iglesias J R, Tönsen K, Graef G, Maier-Hauff K
Institute of Neuropathology, Klinikum Rudolf Virchow, Freie Universität, Berlin.
Acta Neurochir (Wien). 1990;102(3-4):145-8. doi: 10.1007/BF01405430.
The authors report on a 43-year-old male with apparent myelomeningeal encephalitis. The most important clinical symptoms included severe lymphocytosis of the CSF, cranial nerve palsies, obstructive hydrocephalus, progressive coma, and presence of an intramedullary mass causing paraplegia. Neither CSF analysis, nor the intraoperative findings gave evidence of a neoplastic process. Regarding the paraclinical data we supposed a CNS inflammatory process, but autopsy revealed the diagnosis of an intraspinal, leptomeningeal gliomatosis.
作者报告了一名43岁患有明显脊髓脊膜脑脊髓炎的男性患者。最重要的临床症状包括脑脊液严重淋巴细胞增多、颅神经麻痹、梗阻性脑积水、进行性昏迷以及存在导致截瘫的髓内肿块。脑脊液分析和术中发现均未提供肿瘤性病变的证据。关于辅助检查数据，我们推测为中枢神经系统炎症过程，但尸检显示诊断为脊髓内、软脑膜胶质瘤病。
