Hambleton J
Department of Medicine, University of California, San Francisco, USA.
Oncology (Williston Park). 1996 May;10(5):671-80.
Hematologic complications of HIV disease are commonly encountered by physicians and other health-care workers caring for patients infected with this virus. Ineffective hematopoiesis, infiltrative diseases of the bone marrow, nutritional deficiencies, peripheral destruction of blood cells secondary to splenomegaly or immune dysregulation, and drug effects all contribute to the variety of hematologic abnormalities seen in these patients. This review explores the causes of isolated or trilineage cytopenias and coagulopathies; the utility of bone marrow biopsy examination; and the role of colony-stimulating factors as therapeutic agents in patients with HIV disease.
感染人类免疫缺陷病毒（HIV）的患者的血液学并发症，是治疗该病毒感染患者的内科医生及其他医护人员经常遇到的情况。造血功能低下、骨髓浸润性疾病、营养缺乏、继发于脾肿大或免疫失调的血细胞外周破坏以及药物作用，均导致了这些患者出现各种各样的血液学异常。本文综述探讨了单纯性或三系血细胞减少及凝血病的病因；骨髓活检检查的作用；以及集落刺激因子作为治疗药物在HIV感染患者中的作用。
