Resnick D K, Johnson B L, Lovely T J
Department of Neurological Surgery, Presbyterian University Hospital, Pittsburgh, PA 15213-2582, USA.
Acta Neuropathol. 1996;91(5):554-7. doi: 10.1007/s004010050466.
Rosai-Dorfman disease is an idiopathic histocytic proliferative disorder typically characterized by painless cervical adenopathy, fever, and weight loss. Extranodal manifestations are responsible for presentation in approximately 25% of patients. Orbital involvement has been described in about 10% of patients. There have been only 16 reported cases of Rosai-Dorfman disease presenting with an intracranial mass. We report an unusual case of a patient presenting with bilateral orbital tumors as well as multiple intracranial masses. Clinical, magnetic resonance imaging, and histopathological features are discussed.
罗萨伊-多夫曼病是一种特发性组织细胞增生性疾病，典型表现为无痛性颈部淋巴结肿大、发热和体重减轻。结外表现约占25%患者的首发症状。约10%的患者有眼眶受累的报道。仅有16例罗萨伊-多夫曼病表现为颅内肿块的病例报道。我们报告了1例罕见病例，患者表现为双侧眼眶肿瘤及多个颅内肿块。并对其临床、磁共振成像及组织病理学特征进行了讨论。
