Henderson B, Nair S P, Coates A R
Maxillofacial Surgery Research Unit, Eastman Dental Institute for Oral Health Care Sciences, University College London, UK.
Inflamm Res. 1996 Apr;45(4):155-8. doi: 10.1007/BF02285154.
Molecular chaperones are intracellular protein-folding proteins which form part of an ancient cellular response to stress called the heat shock response. They have been the focus for attention during the last decade because of the discovery of their vital role in cell functioning. In very recent years additional roles for these 'topologically-active' proteins in the process of tissue pathology and its treatment have been indicated and are reviewed.
分子伴侣是细胞内的蛋白质折叠蛋白，它们是古老的细胞应激反应（即热休克反应）的一部分。在过去十年中，由于发现它们在细胞功能中起着至关重要的作用，因此一直备受关注。近年来，这些“拓扑活性”蛋白在组织病理学及其治疗过程中的其他作用也已得到证实，并在此进行综述。
