Yamamoto H, Azumi A, Sakai J, Yamamoto M
Department of Ophthalmology, Kobe University School of Medicine, Hyogo, Japan.
Nippon Ganka Gakkai Zasshi. 1996 Jul;100(7):558-61.
The recurrence mechanism of endogenous uveitis remains to be explained, but it is popularly believed that hereditary background and environmental changes affect this mechanism. On Jan 17, 1995, the Hanshin-Awaji distinct in Japan was struck by a major earthquake. Over 6,300 people were killed and more than 310,000 were made homeless. The inhabitants of this area suffered emotional stress from the sudden changes in their living environment. In 116 endogenous uveitis patients who were being followed up for more than 2 years after Jul 17, 1993, at Kobe University Hospital in the stricken area, we investigated the recurrence rate of endogenous uveitis before and after the earthquake. The recurrence rate after the earthquake was significantly higher than before the earthquake (10% vs 3%), and women were more often affected than men after the earthquake. Our data suggests that psychological stress from sudden changes in the living environment after the earthquake can trigger the recurrence of endogenous uveitis. It might be important to provide psychological as well as physical care of endogenous uveitis patients after a disaster.
内因性葡萄膜炎的复发机制尚待阐明，但普遍认为遗传背景和环境变化会影响这一机制。1995年1月17日，日本阪神-淡路地区发生了一场大地震。6300多人丧生，31万多人无家可归。该地区居民因生活环境的突然变化而承受着情绪压力。在受灾地区的神户大学医院，我们对1993年7月17日之后接受了两年多随访的116例内因性葡萄膜炎患者，调查了地震前后内因性葡萄膜炎的复发率。地震后的复发率显著高于地震前（10%对3%），而且地震后女性比男性更常受到影响。我们的数据表明，地震后生活环境的突然变化所产生的心理压力可引发内因性葡萄膜炎的复发。灾难过后，对内因性葡萄膜炎患者提供心理护理以及身体护理可能很重要。
