Yoshikai S, Nagata S, Ohara S, Yuhi F, Sakata S, Matsuno H
Department of Neurosurgery, Iizuka Hospital, Fukuoka, Japan.
No Shinkei Geka. 1996 Aug;24(8):733-8.
The authors report a clinical analysis of the outcomes of aneurysmal subarachnoid hemorrhages in 112 patients. Cerebral angiography was conducted on 85 patients. Clipping or wrapping of the aneurysm was performed on 81 patients. The overall good outcome (GR and MD in the Glasgow Outcome Scale) ratio and mortality rate were 43% and 34%, respectively. The good outcome ratio and mortality rate in operative cases were 59% and 12%, respectively. With regard to the timing of the operation, 77 cases (95%) underwent early operation and 4 cases (5%) underwent delayed operation. The good outcome ratio of patients with grade I to III at surgery using the Hunt and Kosnik grading system was 74%. There was no difference in outcome between the patients with a ruptured aneurysm in the anterior circulation and those with one in the posterior circulation. The retrospective analysis of the overall outcomes showed the risk factors as being: age over 70 years, cerebral atherosclerosis, poor grade on Hunt and Kosnik grading system and symptomatic vasospasm. Preoperative bleeding of the aneurysm, severe brain swelling at surgery, and postoperative symptomatic vasospasm were factors which worsen the outcome of surgically treated patients. Patients with more than 2 factors showed worse outcomes than those with only one factor. The utilization of these prognostic factors should be important to improve the outcome of patients with aneurysmal subarachnoid hemorrhage.
作者报告了112例动脉瘤性蛛网膜下腔出血患者的临床结局分析。85例患者接受了脑血管造影。81例患者进行了动脉瘤夹闭或包裹术。总体良好结局(格拉斯哥结局量表中的GR和MD)比例和死亡率分别为43%和34%。手术病例的良好结局比例和死亡率分别为59%和12%。关于手术时机,77例(95%)接受了早期手术,4例(5%)接受了延期手术。使用Hunt和Kosnik分级系统,手术时I至III级患者的良好结局比例为74%。前循环动脉瘤破裂患者与后循环动脉瘤破裂患者的结局无差异。对总体结局的回顾性分析显示危险因素为:70岁以上、脑动脉粥样硬化、Hunt和Kosnik分级系统分级差以及症状性血管痉挛。动脉瘤术前出血、手术时严重脑肿胀和术后症状性血管痉挛是使手术治疗患者结局恶化的因素。有2个以上因素的患者比只有1个因素的患者结局更差。利用这些预后因素对于改善动脉瘤性蛛网膜下腔出血患者的结局应具有重要意义。