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[运动与尿液成分的测量——肾血流量、电解质、激素以及尿蛋白排泄对运动的反应]

[Sports and measurement of components in urine--responses of renal blood flow, electrolytes and hormones and of excretion of proteins into urine to exercise].

作者信息

Suzuki M, Machida K

机构信息

Department of Laboratory Medicine, Jikeikai University School of Medicine, Tokyo, Japan.

出版信息

Rinsho Byori. 1996 Jul;44(7):627-32.

PMID:8741492
Abstract

Renal blood flow decreased depending on the increase in exercise intensity. The kidneys may have roles to conserve the electrolytes and body fluid, and maintenance of acid-base balance during and after severe exercise. Increases in plasma hormones involved in the regulation of electrolyte-water balance, and decreases in urine flow, Na, Cl and K excretions into urine were observed following moderate exercise under a warm environment. Inhibition of electrolytes and water excretion into urine following exercise in water was less than that following exercise on land. Exercise in water is good for patients with hypertension, obesity and a mild renal disease who have tendency to conserve sodium and/or water. Increase in urinary albumin excretion, glomerular-type proteinuria was observed after moderate exercise (50 approximately 75%HRmax) in the obese individuals who had higher levels of hematocrit, serum concentrations of triglyceride, total cholesterol, LDL-cho, apoprotein B, CIII, and fasting insulin. The findings suggest that moderate exercise causes a latent abnormality of renal glomerular basement membrane in the obese individuals who had an early disturbance of glucose-fatty metabolism.

摘要

肾血流量随运动强度的增加而减少。在剧烈运动期间及之后,肾脏可能具有保存电解质和体液以及维持酸碱平衡的作用。在温暖环境下进行适度运动后,观察到参与调节电解质 - 水平衡的血浆激素增加,以及尿流量、尿中钠、氯和钾排泄量减少。在水中运动后对尿中电解质和水排泄的抑制作用小于在陆地上运动后。水中运动对有钠和/或水潴留倾向的高血压、肥胖和轻度肾病患者有益。在血细胞比容、甘油三酯、总胆固醇、低密度脂蛋白胆固醇、载脂蛋白B、CIII和空腹胰岛素水平较高的肥胖个体中,适度运动(约50 - 75%最大心率)后观察到尿白蛋白排泄增加,出现肾小球型蛋白尿。这些发现表明,适度运动在早期糖脂代谢紊乱的肥胖个体中会导致肾小球基底膜潜在异常。

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