Adachi A, Hasegawa M, Ebihara S
Department of Animal Physiology, Nagoya University, Japan.
Neuroreport. 1995 Dec 29;7(1):286-8.
Ocular melatonin rhythms were measured in pigeons (Columba livia) by in vivo microdialysis. The birds were placed in light-dark cycles with 12 h of light and 12 h of darkness (LD12:12) or continuous dim light (LLdim) after LD12:12. Under LD12:12, melatonin levels were low during the light and high during the dark. The rhythms persisted under LLdim with lower levels during the subjective day and higher levels during the subjective night. Two hours of light exposure in the middle of the night acutely suppressed melatonin to the daytime level. These results indicate that microdialysis is useful for studies investigating the mechanism regulating ocular melatonin rhythms.
通过体内微透析法测定了家鸽（Columba livia）眼部褪黑素的节律。将这些鸟类置于12小时光照和12小时黑暗的明暗循环（LD12:12）中，或在LD12:12之后置于持续弱光（LLdim）环境中。在LD12:12条件下，褪黑素水平在光照期间较低，在黑暗期间较高。在LLdim条件下，这些节律依然存在，在主观白天水平较低，在主观夜间水平较高。在午夜进行两小时的光照会使褪黑素急剧抑制至白天水平。这些结果表明，微透析法对于研究调节眼部褪黑素节律的机制很有用。
