Jaggi M, Mehrotra P K, Maitra S C, Agarwal S L, Das K, Kamboj V P
Division of Endocrinology, Central Drug Research Institute, Lucknow, India.
Reprod Fertil Dev. 1995;7(6):1539-46. doi: 10.1071/rd9951539.
Two cell types, the cyto- and syncytio-trophoblasts, were identified in human chorionic villi of 6-10 weeks' gestation. The intracellular organization of these cells was examined. Ultrathin sections of small pieces of chorionic villi revealed the presence of a multinucleate syncytiotrophoblastic layer, whose surface was covered with microvilli. The cytotrophoblasts, however, had a single large nucleus with a prominent nucleolus. An interesting feature of the basement membrane of these cells was the presence of aggregates of dark granules in samples of the earlier gestational age (6-8 weeks) and granular bodies having a dense outer ring and a translucent inner ring with a lucid central area in samples of 8-10 weeks' gestation. Both types of granules are mineralized and are assumed to perform a buffering role for maintaining the neutrality of the layer.
在妊娠6 - 10周的人绒毛膜绒毛中鉴定出两种细胞类型，即细胞滋养层细胞和合胞体滋养层细胞。对这些细胞的细胞内结构进行了检查。绒毛小块的超薄切片显示存在多核合胞体滋养层，其表面覆盖有微绒毛。然而，细胞滋养层细胞有一个单个的大细胞核，核仁明显。这些细胞基底膜的一个有趣特征是，在妊娠早期（6 - 8周）的样本中存在深色颗粒聚集体，而在妊娠8 - 10周的样本中存在具有致密外环、半透明内环和清晰中心区域的颗粒体。这两种颗粒都矿化了，并被认为起到维持该层中性的缓冲作用。
