Shopova E
Akush Ginekol (Sofiia). 1995;34(3):32-4.
The sensitivity to a given number of antibiotics of 205 strains of enterococci, isolated for a period of one year was studied. The enterococci were isolated from materials, sent for microbiological examination in different clinical settings 55 strains of enterococci from the lower genital tract were tested (vaginal and cervical secretions), 36 strains from the upper genital tract (lochia, peritoneal aspirates, IUD), 8 strains from wounds (perineal and abdominal), 37 strains from urine and 69 strains from the newborns. There was a high sensitivity towards carbenicillin--92.7% towards azlocillin 91.2% and towards ampicillin--83.9% The strains, isolated from gynecologic patients showed increased resistance towards aminoglucosides--49.5% towards gentamycin and 46.5% towards amicacin. The resistance towards gentamicin in the newborns was 68.1%. The strains from urine were resistant to cyprofloxacine in 29.7%. All the enterococci tested were practically resistant to cefamandole and oxacilline. The author suggests that for initial therapy in proven or suspected enterococcal infection carbenicilline, azlocillin and ampicillin. They are suitable both for gynecologic patients and newborns. The aminoglucosides have to be administrated after testing because of the significant resistance found for the different strains. The same is true for erythromycin and cyprofloxacine
对一年内分离出的205株肠球菌对一定数量抗生素的敏感性进行了研究。这些肠球菌从不同临床环境中送去进行微生物检查的材料中分离得到。对55株来自下生殖道（阴道和宫颈分泌物）的肠球菌进行了测试，36株来自上生殖道（恶露、腹腔穿刺液、宫内节育器），8株来自伤口（会阴和腹部），37株来自尿液，69株来自新生儿。对羧苄青霉素的敏感性较高——对阿洛西林为92.7%，对氨苄青霉素为91.2%，对氨苄西林为83.9%。从妇科患者中分离出的菌株对氨基糖苷类抗生素的耐药性增加——对庆大霉素为49.5%，对丁胺卡那霉素为46.5%。新生儿中对庆大霉素的耐药性为68.1%。来自尿液的菌株对环丙沙星的耐药率为29.7%。所有测试的肠球菌实际上对头孢孟多和苯唑西林耐药。作者建议，对于已证实或疑似肠球菌感染的初始治疗，可使用羧苄青霉素、阿洛西林和氨苄西林。它们对妇科患者和新生儿都适用。由于不同菌株存在显著耐药性，氨基糖苷类抗生素必须在测试后使用。红霉素和环丙沙星也是如此。
