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[晚期清理切尔诺贝利原子能发电站事故善后人员的肺泡巨噬细胞的形态学特征(1)]

[The morphological characteristics of the alveolar macrophages in those who cleaned up the aftermath of the accident at the Chernobyl Atomic Electric Power Station at a late period (1)].

作者信息

Cherniaev A L, Charpin C, Grobova O M, Hoffshir D, Dmitrov E M, Aĭsanov Z R, Charpin D, Voisin C

出版信息

Ter Arkh. 1996;68(3):19-23.

PMID:8744096
Abstract

The paper presents morphological, morphometric and densitometric evidence obtained on cytoplasmic inclusions of alveolar macrophages from bronchoalveolar lavage of chronic obstructive bronchitis (COB) sufferers. All of them previously worked in the zone contaminated after the Chernobyl accident. The control consisted of nonexposed to radiation COB patients. In the exposed subjects alveolar macrophages were more active, 20% of cytoplasm was occupied by numerous phagolysosomes varying in form. Their densitometric evaluation has been performed. Further bronchoalveolar lavages will be conducted to follow up the above changes in alveolar macrophages.

摘要

本文展示了从慢性阻塞性支气管炎(COB)患者支气管肺泡灌洗获得的肺泡巨噬细胞胞质内含物的形态学、形态计量学和密度测定证据。所有患者此前都曾在切尔诺贝利事故后受污染地区工作。对照组为未接触辐射的COB患者。在受辐射的受试者中,肺泡巨噬细胞更活跃,20%的细胞质被大量形态各异的吞噬溶酶体占据。已对其进行了密度测定评估。后续将进行进一步的支气管肺泡灌洗,以跟踪肺泡巨噬细胞的上述变化。

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