Scott W G, Klug A
MRC Laboratory of Molecular Biology, Cambridge, UK.
Trends Biochem Sci. 1996 Jun;21(6):220-4.
The hammerhead RNA is a small catalytic RNA found in a number of RNA virus genomes and virus-like RNAs. The recently determined crystal structures of hammerhead ribozymes reveal how a small RNA motif can fold up into a conformation suitable for mediating RNA cleavage.
锤头状RNA是一种小型催化RNA,存在于许多RNA病毒基因组和类病毒RNA中。最近确定的锤头状核酶晶体结构揭示了一个小RNA基序如何折叠成适合介导RNA切割的构象。