Massy Z A, Kasiske B L
Division of Nephrology, Hennepin County Medical Center, University of Minnesota Medical School, Minneapolis 55415, USA.
Curr Opin Nephrol Hypertens. 1996 Mar;5(2):141-6. doi: 10.1097/00041552-199603000-00007.
Dyslipidemia is common in patients with renal disease, may contribute to the high incidence of cardiovascular disease, and may play a role in progressive renal injury. Recent studies have shown that newer antilipemic agents appear to be safe and effective in patients with renal disease. This should make it possible to conduct large, controlled clinical trials examining the effect of lipid-lowering strategies on cardiovascular disease, and on renal disease progression.
血脂异常在肾病患者中很常见,可能导致心血管疾病的高发病率,并且可能在进行性肾损伤中起作用。最近的研究表明,新型降脂药物在肾病患者中似乎是安全有效的。这应该能够开展大型对照临床试验,以研究降脂策略对心血管疾病以及肾病进展的影响。