Rosner M, Bronshtein M, Leikomovitz P, Berkenstat M, Barkai G, Barishak R Y
Eye Pathology Laboratory, Goldschleger Eye Institute, Sackler Faculty of Medicine, Tel Aviv University, Tel-Hashomer, Israel.
Eur J Ophthalmol. 1996 Jan-Mar;6(1):90-3. doi: 10.1177/112067219600600118.
Transvaginal ultrasonography is a relatively new technique for visualizing the orbits in a fetus of 4 to 5 cm. At fifteen weeks of gestation it is possible to recognize the lenses and the hyaloid arteries in the eyes, to diagnose structural malformations such as anophthalmos, microphthalmos, buphthalmos and moderate to severe cataract. In most cases cataracts were associated with intracranial defects. We describe a case where the sonographic diagnosis of fetal cataract was confirmed by histopathological examination. A 27-year-old woman had a routine transvaginal sonography at 15 weeks' normal gestation. Microphthalmos without a hyaloid artery and disorganization of the anterior chamber and lens consistent with cataract were demonstrated in the fetal left eye. In accordance with the parents' decision, the pregnancy was terminated a week later. Autopsy of the fetus was done and serial sections of the left eye were studied by light microscopy. Histopathological examination verified the sonographic diagnosis of fetal cataract in a microphthalmic eye. Associated findings included malformation of the anterior segment and retinal dysplasia.
经阴道超声检查是一种相对较新的技术，用于观察4至5厘米胎儿的眼眶。在妊娠15周时，可以识别眼睛中的晶状体和玻璃体动脉，诊断诸如无眼、小眼、牛眼和中度至重度白内障等结构畸形。在大多数情况下，白内障与颅内缺陷有关。我们描述了一例胎儿白内障的超声诊断经组织病理学检查得到证实的病例。一名27岁女性在妊娠15周正常产检时进行了常规经阴道超声检查。胎儿左眼显示小眼畸形，无玻璃体动脉，前房和晶状体结构紊乱，符合白内障表现。根据父母的决定，一周后终止妊娠。对胎儿进行了尸检，并通过光学显微镜对左眼进行了连续切片研究。组织病理学检查证实了小眼畸形眼中胎儿白内障的超声诊断。相关发现包括前段畸形和视网膜发育异常。
