奇异变形杆菌和普通变形杆菌中超氧化物歧化酶的产生
Production of superoxide dismutases from Proteus mirabilis and Proteus vulgaris.
作者信息
Dayton T M, Diefenbach K A, Fuller M L, Valtos J, Niederhoffer E C
机构信息
Department of Chemistry, Southern Illinois University of Carbondale, USA.
出版信息
Biometals. 1996 Apr;9(2):131-7. doi: 10.1007/BF00144617.
Proteus mirabilis and Proteus vulgaris expressed a combination of superoxide dismutase (Sod) activities, which was assigned to FeSod1, FeSod2 and MnSod for P. mirabilis, and FeSod, MnSod and CuZnSod for P. vulgaris. Production of the Sod proteins was dependent on the availability of iron, whether cells were grown under anaerobiosis or aerobiosis and growth phase. Nalidixic acid and chloramphenicol inhibited cell growth and the iron- and dioxygen-dependent production of Sod. These results support the involvement of metal ions and redox status in the production of Proteus Sods.
奇异变形杆菌和普通变形杆菌表达了多种超氧化物歧化酶（Sod）活性组合，其中奇异变形杆菌的这些活性分别归属于FeSod1、FeSod2和MnSod，普通变形杆菌的则归属于FeSod、MnSod和CuZnSod。Sod蛋白的产生取决于铁的可利用性，无论细胞是在厌氧还是需氧条件下生长以及处于何种生长阶段。萘啶酸和氯霉素抑制细胞生长以及铁和双加氧依赖的Sod产生。这些结果支持金属离子和氧化还原状态参与变形杆菌Sods的产生。
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