Arfsten D P, Schaeffer D J, Mulveny D C
Karch & Associates, Inc., Washington, DC 20006, USA.
Ecotoxicol Environ Saf. 1996 Feb;33(1):1-24. doi: 10.1006/eesa.1996.0001.
Polycyclic aromatic hydrocarbons (PAHs) are common contaminants of terrestrial and aquatic ecosystems. Traditional, toxicological studies for defining the potential hazard of PAHs in wildlife have been conducted in the absence of UV radiation. However, recent toxicology studies particularly in the discipline of aquatic toxicology have presented evidence that PAHs may become toxic or substantially more toxic upon coexposure to UV light (300-400 nm). In this paper, a comprehensive review of the literature pertaining to the toxicological interaction of PAHs and UV light in aquatic and terrestrial organisms is presented. It is concluded that the acute phototoxic effects of PAHs should be considered when conducting environmental risk assessments; however, more research needs to be conducted to address the lack of data on the enhancement of UV-induced carcinogenesis by PAH compounds.
多环芳烃（PAHs）是陆地和水生生态系统中常见的污染物。传统上，在没有紫外线辐射的情况下开展了确定PAHs对野生动物潜在危害的毒理学研究。然而，最近的毒理学研究，特别是水产毒理学领域的研究表明，多环芳烃在同时暴露于紫外线（300-400纳米）时可能变得有毒或毒性大幅增加。本文全面综述了有关多环芳烃与紫外线在水生和陆地生物中毒理学相互作用的文献。得出的结论是，在进行环境风险评估时应考虑多环芳烃的急性光毒性效应；然而，由于缺乏关于多环芳烃化合物增强紫外线诱导致癌作用的数据，还需要开展更多的研究。
