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“异染色质”(H字)的回归。

Return of the H-word (heterochromatin).

作者信息

Lohe A R, Hilliker A J

机构信息

Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

出版信息

Curr Opin Genet Dev. 1995 Dec;5(6):746-55. doi: 10.1016/0959-437x(95)80007-r.

Abstract

Recent advances in studies of yeast, Drosophila and humans have renewed interest in heterochromatin. These recent studies have demonstrated the interspersion and rapid spread of transposable elements into Drosophila heterochromatin; documented the requirement of heterochromatic genes for heterochromatin; identified heterochromatin-like regions in yeast chromosomes; confirmed an important role for satellite DNA in human centromere function; and suggested potential functions for heterochromatin-associated proteins.

摘要

酵母、果蝇和人类研究的最新进展重新唤起了人们对异染色质的兴趣。这些最新研究表明转座元件散布并迅速扩散到果蝇异染色质中;记录了异染色质基因对异染色质的需求;在酵母染色体中鉴定出类异染色质区域;证实了卫星DNA在人类着丝粒功能中的重要作用;并提出了异染色质相关蛋白的潜在功能。

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