Lohe A R, Hilliker A J
Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts 02138, USA.
Curr Opin Genet Dev. 1995 Dec;5(6):746-55. doi: 10.1016/0959-437x(95)80007-r.
Recent advances in studies of yeast, Drosophila and humans have renewed interest in heterochromatin. These recent studies have demonstrated the interspersion and rapid spread of transposable elements into Drosophila heterochromatin; documented the requirement of heterochromatic genes for heterochromatin; identified heterochromatin-like regions in yeast chromosomes; confirmed an important role for satellite DNA in human centromere function; and suggested potential functions for heterochromatin-associated proteins.
酵母、果蝇和人类研究的最新进展重新唤起了人们对异染色质的兴趣。这些最新研究表明转座元件散布并迅速扩散到果蝇异染色质中；记录了异染色质基因对异染色质的需求；在酵母染色体中鉴定出类异染色质区域；证实了卫星DNA在人类着丝粒功能中的重要作用；并提出了异染色质相关蛋白的潜在功能。
