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转座元件在黑腹果蝇中以一种保守的分布模式定位,这种模式从β异染色质延伸到着丝粒。

Transposable elements map in a conserved pattern of distribution extending from beta-heterochromatin to centromeres in Drosophila melanogaster.

作者信息

Carmena M, González C

机构信息

Department of Anatomy and Physiology, CRC Cell Cycle Genetics Group, Medical Sciences Institute. The University of Dundee, Dundee DD14HN, Scotland.

出版信息

Chromosoma. 1995 Jul;103(10):676-84. doi: 10.1007/BF00344228.

DOI:10.1007/BF00344228
PMID:7664614
Abstract

In situ hybridisation to mitotic chromosomes shows that sequences homologous to different Drosophila melanogaster transposable elements are widely distributed not only in beta but also in alpha-heterochromatin. Clusters of these sequences are detected in most proximal positions. They colocalise with known satellite sequences in several regions, but are also located in places where no known sequence has been mapped so far. The pattern of hybridisation is dinstinctive and specific for each element, and presents constant features in six different D. melanogaster strains studied. The entirely heterochromatic Y chromosome contains large amounts of these sequences. Additionally, some of these sequences appear to be present in substantial quantities in the smallest minichromosome of Drosophila, Dp(1;f)1187.

摘要

对有丝分裂染色体的原位杂交显示,与不同黑腹果蝇转座元件同源的序列不仅广泛分布于β异染色质,也分布于α异染色质。在大多数近端位置检测到这些序列的簇。它们在几个区域与已知卫星序列共定位,但也位于迄今尚无已知序列定位的地方。每个元件的杂交模式都是独特且特异的,并且在所研究的六个不同黑腹果蝇品系中呈现出恒定的特征。完全异染色质的Y染色体含有大量这些序列。此外,其中一些序列似乎在果蝇最小的微型染色体Dp(1;f)1187中大量存在。

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