Optimization of implantation in the in-vitro fertilization laboratory.

Implantation failure rates after in-vitro fertilization (IVF) can be reduced in the IVF laboratory using two different techniques: assisted hatching and embryo co-culture on monolayer feeder cells. A review of the different methodologies and the results gained using these techniques is reported. Preliminary results obtained in the Reproductive Medicine Service of the Institut Universitari Dexeus, Barcelona, Spain using these techniques are also presented.