Wang Y, Chang W, Pu D
First Affiliated Hospital, China Medical University, Shenyang.
Zhonghua Fu Chan Ke Za Zhi. 1997 Apr;32(4):226-8.
To analyse the clinical characteristics and prognosis of primary malignant melanoma in female genital tract.
Clinical data of 15 patients with primary malignant genital melanoma were analysed retrospectively. The tumors occurred in the vulva (4 patients), in vagina (9) and in uterine cervix (2). 11 of them were treated by surgery combined with chemotherapy and immunotherapy, the remaining 4 by chemotherapy and immunotherapy only.
All cases except one were followed up. The survival periods were shorter than 1 year in 5 patients, shorter than 2 years in 7. Two were alive for more than 3 years and 1 for more than 19 years.
The prognosis of primary malignant melanoma is rather poor. Surgery combined of chemotherapy and immunotherapy is the main therapeutic approach.
分析女性生殖道原发性恶性黑色素瘤的临床特征及预后。
回顾性分析15例原发性恶性生殖道黑色素瘤患者的临床资料。肿瘤发生于外阴（4例）、阴道（9例）和子宫颈（2例）。其中11例采用手术联合化疗及免疫治疗，其余4例仅采用化疗及免疫治疗。
除1例失访外，其余病例均获随访。5例患者生存期短于1年，7例短于2年。2例存活超过3年，1例存活超过19年。
原发性恶性黑色素瘤预后较差。手术联合化疗及免疫治疗是主要治疗方法。
