Omotainse S O, Anosa V O
Department of Veterinary Pathology, University of Ibadan, Nigeria.
Rev Elev Med Vet Pays Trop. 1995;48(3):254-8.
Three dogs were subcutaneously infected with Trypanosoma brucei strain ILRAD 1797. Artificial haemolytic anaemia was induced in 2 other dogs by phlebotomy, heat treatment and re-infusion of the blood, while 2 dogs were kept as control animals. The infected animals developed pan-leucopenia and thrombocytopenia, while the dogs with artificial haemolytic anaemia developed leucocytosis and thrombocytosis. These findings suggest that there was a bone marrow depressing factor in the plasma of T. brucei-infected dogs especially as it affected leucocyte production.
三只狗皮下感染了布氏锥虫ILRAD 1797株。通过放血、热处理和血液回输在另外两只狗身上诱发了人工溶血性贫血，同时将两只狗作为对照动物。感染的动物出现了全血细胞减少和血小板减少，而患有人工溶血性贫血的狗出现了白细胞增多和血小板增多。这些发现表明，布氏锥虫感染的狗的血浆中存在一种骨髓抑制因子，尤其是对白细胞生成的影响。
