Hirshberg A, Buchner A
Section of Oral Pathology and Oral Medicine, Tel Aviv University, Israel.
Eur J Cancer B Oral Oncol. 1995 Nov;31B(6):355-60. doi: 10.1016/0964-1955(95)00031-3.
Metastatic tumours to the oral region are uncommon. There are more published cases of jawbone metastases than in oral soft tissues. The most common primary sources of metastatic tumours to the oral region are the breast, lung, kidney, bone and colon. The breast is the most common primary site for tumours metastasising to the jawbones, whereas the lung is the most common source for metastases to the oral soft tissues. In the jawbones, the common location of the metastatic lesions is the mandible, with the molar area being the most frequent involved site. In the oral soft tissues, the attached gingiva is the most common affected site followed by the tongue. In nearly 30% of cases, the metastatic lesion in the oral region is the first indication of an undiscovered malignancy at a distant site. The biological basis of the metastatic process is discussed.
口腔区域的转移性肿瘤并不常见。与口腔软组织相比，颌骨转移的病例报道更多。口腔区域转移性肿瘤最常见的原发部位是乳腺、肺、肾、骨和结肠。乳腺是肿瘤转移至颌骨最常见的原发部位，而肺是转移至口腔软组织最常见的来源。在颌骨中，转移性病变的常见部位是下颌骨，磨牙区是最常受累的部位。在口腔软组织中，附着龈是最常见的受累部位，其次是舌。在近30%的病例中，口腔区域的转移性病变是远处未被发现的恶性肿瘤的首个迹象。本文讨论了转移过程的生物学基础。
