Soualem H, Benjelloun L
Oral Surgery Department, Dental Consultation and Treatment Center, Faculty of Dental Medicine, University Mohamed V, Rabat, Morocco.
Oral Surgery Department, Dental Consultation and Treatment Center, Faculty of Dental Medicine, University Mohamed V, Rabat, Morocco.
Int J Surg Case Rep. 2024 Sep;122:110110. doi: 10.1016/j.ijscr.2024.110110. Epub 2024 Aug 3.
Breast cancer is the most common cancer in women and the second leading cause of cancer-related death. Breast cancer manifestations in the head and neck are relatively rare, have greater predilection for the jaws than for soft tissues. Metastasis in the oral cavity account for only 1 to 3 % of all oral malignant lesions. Regardless of the rare occurrence of metastatic lesions to the jaw, it should be taken into consideration in the individuals with a history of malignancy.
The article reports a rare case of metastatic lesion of breast cancer to unilateral mandibular ramus region. The 66-year-old female patient was complaining of pain and swelling in the right mandible angle. She was referred to our department by her oncologist with the differential diagnosis of osteonecrosis or metastasis. She had undergone radical mastectomy for invasive lobular carcinoma of the left breast without adjuvant treatment. Oral cavity examination did not reveal the existence of any ulcer or fistula. Based on the patient's medical history and paresthesia of the lower lip and chin, the metastatic disease was highly suspected. The patient was referred to her oncologist for chemotherapy treatment before any invasive surgical management.
Breast cancer (BC) is the most common cancer affecting women globally. Bone is the most common site of metastasis in BC patients, with up to 75 % of stage IV BC patients developing skeletal metastasis. The frequent metastatic sites of bone are spine, ribs, sternum, femur, pelvis. Breast carcinoma metastasizes to the jaw bones are uncommon.
The diagnosis of metastasis to the oral cavity is a significant challenge to the clinician due to the lack of pathognomonic signs and symptoms. The general dentist or dental specialist should maintain a high level of suspicion while dealing patients with a history of cancer.
乳腺癌是女性最常见的癌症，也是癌症相关死亡的第二大主要原因。乳腺癌在头颈部的表现相对罕见，相较于软组织，更易发生于颌骨。口腔转移瘤仅占所有口腔恶性病变的1%至3%。尽管颌骨转移瘤罕见，但对于有恶性肿瘤病史的个体仍应予以考虑。
本文报道了一例罕见的乳腺癌转移至单侧下颌支区域的病例。该66岁女性患者主诉右下颌角疼痛和肿胀。她被肿瘤内科医生转诊至我科，鉴别诊断为骨坏死或转移瘤。她曾因左乳浸润性小叶癌接受根治性乳房切除术，未接受辅助治疗。口腔检查未发现任何溃疡或瘘管。基于患者的病史以及下唇和下巴的感觉异常，高度怀疑为转移性疾病。在进行任何侵入性手术治疗之前，该患者被转诊至肿瘤内科医生处接受化疗。
乳腺癌是全球影响女性最常见的癌症。骨是乳腺癌患者最常见的转移部位，高达75%的IV期乳腺癌患者会发生骨转移。常见的骨转移部位是脊柱、肋骨、胸骨、股骨、骨盆。乳腺癌转移至颌骨并不常见。
由于缺乏特异性的体征和症状，口腔转移瘤的诊断对临床医生来说是一项重大挑战。普通牙医或牙科专家在诊治有癌症病史的患者时应保持高度怀疑。
