Hyett J, Moscoso G, Nicolaides K
Harris Birthright Research Centre for Fetal Medicine, King's College Hospital Medical School, London, UK.
Hum Reprod. 1995 Nov;10(11):3049-51. doi: 10.1093/oxfordjournals.humrep.a135845.
Pathological examination of the great vessels was performed in 34 trisomy 21 fetuses after surgical termination of pregnancy at 11-16 weeks of gestation. In each case, the external diameters of eight segments of the great vessels were measured. The aortic valve and the ascending aorta were wider than in normal fetuses, whilst the aortic isthmus was narrower. The degree of narrowing of the isthmus was significantly greater in fetuses with high nuchal translucency thickness and it is possible that there is a causal association between the two.
对34例孕11 - 16周手术终止妊娠的21三体胎儿的大血管进行了病理检查。在每例中，测量了大血管八个节段的外径。主动脉瓣和升主动脉比正常胎儿宽，而主动脉峡部较窄。颈部半透明厚度高的胎儿峡部狭窄程度明显更大，两者之间可能存在因果关系。
