Huang F Y, Tsai T C
Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan.
Pediatr Nephrol. 1995 Dec;9(6):715-7. doi: 10.1007/BF00868720.
A retrospective study was performed to evaluate the results of medical management of primary vesicoureteral reflux (VUR) in infants and children. The charts of 105 patients (74 boys, 31 girls) with 167 refluxing ureters were reviewed. The age at diagnosis ranged from 3 days to 9.2 years (mean 1.3 +/- 1.9 years). The mean duration of follow-up was 2.4 +/- 1.5 years. We found that the patient's sex did not influence the fate of VUR and its complications. Patients whose reflux improved while being managed medically were younger than those who did not improve, and the younger the patient the sooner the reflux resolved. Improvement and resolution of reflux were also related to grade, and the lower the initial grading the sooner the reflux resolved. Spontaneous resolution rates of reflux were 92.3%, 76.2%, 61.7%, and 32.0% for grades I, II, III, and IV, respectively. No ureters with grade V reflux resolved without complications. The most common complications in our series were renal scarring and secondary obstructive uropathy.
进行了一项回顾性研究，以评估婴幼儿原发性膀胱输尿管反流（VUR）的药物治疗效果。回顾了105例患者（74例男孩，31例女孩）共167条反流输尿管的病历。诊断时年龄为3天至9.2岁（平均1.3±1.9岁）。平均随访时间为2.4±1.5年。我们发现患者的性别不影响VUR及其并发症的转归。药物治疗期间反流改善的患者比未改善的患者年龄小，患者年龄越小，反流消退越早。反流的改善和消退也与分级有关，初始分级越低，反流消退越早。I、II、III和IV级反流的自发消退率分别为92.3%、76.2%、61.7%和32.0%。无V级反流输尿管在无并发症的情况下消退。我们系列中最常见的并发症是肾瘢痕形成和继发性梗阻性尿路病。
