Bechgaard H, Jespersen S
J Pharm Sci. 1977 Jun;66(6):871-2. doi: 10.1002/jps.2600660635.
By using the GI tube technique, niacin was shown to be equally well absorbed from the stomach and the upper small intestine. The maximum plasma niacin concentrations occurred 10-20 and 5-10 min, respectively, after instillation. Thus, the physiological prerequisites for a physically retarded niacin preparation were established.
通过使用胃肠管技术，研究表明烟酸在胃和小肠上段的吸收情况相同。分别在滴注后10 - 20分钟和5 - 10分钟出现血浆烟酸浓度最大值。因此，确定了制备物理缓释烟酸制剂的生理前提条件。
