Salvati M, Cervoni L, Paolini S, Delfini R
Department of Neurological Sciences, La Sapienza University of Rome, Italy.
Acta Neurochir (Wien). 1995;133(3-4):181-3. doi: 10.1007/BF01420071.
The authors report 34 cases of solitary cerebral metastases from intestinal cancer. In 24 cases the tumour was localized in the colonrectum and in 10 in the small intestine. In 8 patients (23%) neurological symptoms were the first clinical sign of systemic spread of the tumour; in 26 cases (77%) there was a long interval between treatment of the primary and appearance of the cerebral metastasis (average 24 months). Average survival was 10 months and was influenced solely by staging of the primary. Interestingly, the prognostic value of radiotherapy was minimal and none of the patients operated by the "no touch technique" presented with a recurrence.
作者报告了34例来自肠癌的孤立性脑转移病例。其中24例肿瘤位于结肠直肠,10例位于小肠。8例患者(23%)的神经症状是肿瘤全身播散的首个临床体征;26例患者(77%)在原发性肿瘤治疗和脑转移出现之间存在较长间隔(平均24个月)。平均生存期为10个月,且仅受原发性肿瘤分期的影响。有趣的是,放疗的预后价值极小,采用“无接触技术”手术的患者均未出现复发。