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类风湿关节炎中的枕颈固定术——163例患者手术风险因素分析

Occipito-cervical fixation in rheumatoid arthritis--an analysis of surgical risk factors in 163 patients.

作者信息

Zygmunt S C, Christensson D, Säveland H, Rydholm U, Alund M

机构信息

Department of Neurosurgery, University Hospital Lund, Sweden.

出版信息

Acta Neurochir (Wien). 1995;135(1-2):25-31. doi: 10.1007/BF02307410.

Abstract

163 patients with rheumatoid arthritis (RA) and atlanto-axial subluxation treated by posterior occipito-cervical fixation (OCF) over a period of twenty-one years (November 1970-January 1991) were followed. Common complaints prior to surgery were occipital headache, neck pain, radicular pain and myelopathy. The mean age at time of surgery was 61 years. The mean follow-up time was 54 months. Clinical improvement was obtained in 88% of the patients, whereas 7% were unchanged and 5% had progressive symptoms in spite of surgery. There was no pre-operative or immediate postoperative mortality. In 79 patients, one or more potential surgical risk factors were identified. Twenty-four reoperations were performed in the neck. The most common cause for reoperation was mechanical failure due to wire-break or spinous process fracture. Wound infection in the neck was recorded in 16 patients. Five were deep and required removal of the fixation material. Following OCF, new or progressive subaxial subluxation (SAS) led to further surgery in 4%. The study offers support for the beneficial effect of OCF in rheumatoid AAS. We conclude that, in spite of a number of identified risk factors, OCF with the Brattström-Granholm technique remains a safe and effective method for stabilization of upper cervical subluxations in RA.

摘要

对163例类风湿性关节炎(RA)合并寰枢椎半脱位患者在21年期间(1970年11月至1991年1月)采用后路枕颈固定(OCF)治疗并进行随访。术前常见症状为枕部头痛、颈部疼痛、神经根性疼痛和脊髓病。手术时的平均年龄为61岁。平均随访时间为54个月。88%的患者临床症状改善,7%无变化,5%尽管接受了手术仍有症状进展。术前及术后即刻均无死亡病例。79例患者中,发现一个或多个潜在手术风险因素。颈部进行了24次再次手术。再次手术最常见的原因是钢丝断裂或棘突骨折导致的机械故障。16例患者记录有颈部伤口感染。5例为深部感染,需要取出固定材料。OCF术后,4%的患者因新出现或进展性的下颈椎半脱位(SAS)而需要进一步手术。本研究支持OCF对类风湿性AAS的有益作用。我们得出结论,尽管存在一些已确定的风险因素,但采用Brattström-Granholm技术的OCF仍然是稳定类风湿性关节炎上颈椎半脱位的一种安全有效的方法。

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