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类风湿性颈椎病

Rheumatoid cervical myelopathy.

作者信息

Marks J S, Sharp J

出版信息

Q J Med. 1981 Summer;50(199):307-19.

PMID:7330168
Abstract

The mode of presentation and the factors which influenced the diagnosis and outcome in 31 patients with rheumatoid cervical myelopathy were reviewed. The presenting features included paraesthesiae and /or numbness (23 cases) weakness (six) flexor spasms (five) and incontinence (two). Isolated sensory loss presenting in a glove and stocking distribution was often misdiagnosed as a peripheral neuropathy. Multiple neurological deficits were eventually present in all patients and included spastic quadriparesis (17), spastic paraparesis (seven), bladder disturbance (nine), and cranial nerve deficits (six). Twenty-seven patients had impaired light touch and pin prick sensation but the sensory level did not correlate with the presumed level of spinal cord compressions. Twenty-one patients had dissociation between loss of position and vibration sensation. All patients had one or more cervical luxations; five patients had atlanto-axial luxation alone, five had subaxial luxation alone and the remainder multiple luxations. Neurological improvement was more frequent and of longer duration in those treated by occipito-cervical fusion than in those treated conservatively but fitness for surgery may have selected a group with a better prognosis.

摘要

回顾了31例类风湿性颈椎病患者的临床表现以及影响诊断和预后的因素。主要症状包括感觉异常和/或麻木(23例)、无力(6例)、屈肌痉挛(5例)和大小便失禁(2例)。呈手套和袜套样分布的单纯感觉丧失常被误诊为周围神经病变。所有患者最终均出现多种神经功能缺损,包括痉挛性四肢瘫(17例)、痉挛性截瘫(7例)、膀胱功能障碍(9例)和颅神经缺损(6例)。27例患者存在轻触觉和针刺觉减退,但感觉平面与推测的脊髓受压平面不相关。21例患者存在位置觉和振动觉分离。所有患者均有一处或多处颈椎脱位;5例患者仅存在寰枢椎脱位,5例仅存在下颈椎脱位,其余患者为多处脱位。与保守治疗的患者相比,枕颈融合术治疗的患者神经功能改善更频繁且持续时间更长,但适合手术的患者可能预后较好。

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