Phillips M, Greenberg J, Andrzejewski J
Menssana Research, Inc, Fort Lee, New Jersey, USA.
Alcohol Clin Exp Res. 1995 Dec;19(6):1547-9. doi: 10.1111/j.1530-0277.1995.tb01022.x.
The Alcopatch is an improved transdermal dosimeter for the measurement of alcohol consumption, by detection of ethanol in fluid excreted from the skin. The device is worn as a band around the ankle and provides a visual signal in the event of tampering.
Fourteen volunteers wore duplicate Alcopatches for a period of 7 or 8 days, while keeping a written record of their beverage alcohol consumption. Ethanol concentration in the Alcopatch was measured by gas chromatography and correlated with self-reported consumption.
All alcohol consumption in excess of 0.25 g/kg/day resulted in measurable levels of ethanol in the Alcopatch. A positive correlation was observed between the reported consumption of ethanol (in g/kg/day) and the concentration of ethanol in the Alcopatch (square root, in mg/dl) (y = 0.91x + 0.28, r = 0.61) in 12 of 14 subjects.
The Alcopatch detected the consumption of beverage alcohol with high sensitivity and specificity over a period of 7 to 8 days and may be useful for the study of target populations.
酒精贴片是一种经过改进的透皮剂量计，通过检测皮肤排出液中的乙醇来测量酒精摄入量。该装置作为一条带子佩戴在脚踝上，在发生篡改时会发出视觉信号。
14名志愿者佩戴两个酒精贴片，为期7或8天，同时记录他们饮用含酒精饮料的情况。通过气相色谱法测量酒精贴片中的乙醇浓度，并将其与自我报告的摄入量进行关联。
所有超过0.25克/千克/天的酒精摄入量都会导致酒精贴片中出现可测量水平的乙醇。在14名受试者中的12名中，观察到报告的乙醇摄入量（克/千克/天）与酒精贴片中乙醇浓度（平方根，毫克/分升）之间存在正相关（y = 0.91x + 0.28，r = 0.61）。
酒精贴片在7至8天的时间内以高灵敏度和特异性检测到了含酒精饮料的摄入量，可能对目标人群的研究有用。
