Bastos A C, Korah I P, Cendes F, Melanson D, Tampieri D, Peters T, Dubeau F, Andermann F
Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada.
Magn Reson Imaging. 1995;13(8):1107-12. doi: 10.1016/0730-725x(95)02019-p.
In an attempt to better delineate the abnormalities associated with focal cortical dysgenesis, we performed curvilinear reformatting of the cortex from 3D magnetic resonance (MR) images. Illustrative patients with partial seizures and conventional orthogonal MRI evaluation show that small regions of cortical thickening suggestive of focal dysplastic lesions may not be recognized. In three such patients the curvilinear reformatting demonstrated two additional focal abnormalities of the cortical gyri and better defined the two focal lesions found on conventional orthogonal MR images. This method promises to be a useful tool in the evaluation of epileptic patients with proven or suspected subtle structure cortical abnormalities, particularly focal neuronal migration disorders where cortical thickening, abnormal gyral pattern, and poor delineation of the gray-white matter transition are the main findings.
为了更好地描绘与局灶性皮质发育异常相关的异常情况，我们对三维磁共振（MR）图像中的皮质进行了曲线重新格式化处理。有部分性癫痫发作且接受传统正交MRI评估的典型患者显示，提示局灶性发育异常病变的皮质增厚小区域可能无法被识别。在3例此类患者中，曲线重新格式化显示皮质脑回还有另外两个局灶性异常，并更清晰地界定了在传统正交MR图像上发现的两个局灶性病变。该方法有望成为评估已证实或疑似存在细微结构皮质异常的癫痫患者的有用工具，尤其是在局灶性神经元迁移障碍中，主要表现为皮质增厚、脑回模式异常以及灰白质过渡区界限不清。
