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将儿科脑MRI进行曲面重建成“平面地球图”——一种用于显示缺氧缺血性脑病导致的皮质表面萎缩的标准化方法。

Curved reformat of the paediatric brain MRI into a 'flat-earth map' - standardised method for demonstrating cortical surface atrophy resulting from hypoxic-ischaemic encephalopathy.

作者信息

Simpson Ewan, Andronikou Savvas, Vedajallam Schadie, Chacko Anith, Thai Ngoc Jade

机构信息

Department of Pediatric Radiology, Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol, BS2 8BJ, UK.

CRICBristol, University of Bristol, Bristol, UK.

出版信息

Pediatr Radiol. 2016 Sep;46(10):1482-8. doi: 10.1007/s00247-016-3638-3. Epub 2016 Jun 23.

DOI:10.1007/s00247-016-3638-3
PMID:27337989
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5009174/
Abstract

Hypoxic-ischaemic encephalopathy is optimally imaged with brain MRI in the neonatal period. However neuroimaging is often also performed later in childhood (e.g., when parents seek compensation in cases of alleged birth asphyxia). We describe a standardised technique for creating two curved reconstructions of the cortical surface to show the characteristic surface changes of hypoxic-ischaemic encephalopathy in children imaged after the neonatal period. The technique was applied for 10 cases of hypoxic-ischaemic encephalopathy and also for age-matched healthy children to assess the visibility of characteristic features of hypoxic-ischaemic encephalopathy. In the abnormal brains, fissural or sulcal widening was seen in all cases and ulegyria was identifiable in 7/10. These images could be used as a visual aid for communicating MRI findings to clinicians and other interested parties.

摘要

缺氧缺血性脑病在新生儿期通过脑部磁共振成像(MRI)能得到最佳成像。然而,神经影像学检查在儿童期后期也经常进行(例如,当父母在所谓的出生窒息病例中寻求赔偿时)。我们描述了一种标准化技术,用于创建皮质表面的两个曲面重建,以显示新生儿期后成像的儿童缺氧缺血性脑病的特征性表面变化。该技术应用于10例缺氧缺血性脑病病例以及年龄匹配的健康儿童,以评估缺氧缺血性脑病特征的可见性。在异常大脑中,所有病例均可见脑沟或脑裂增宽,10例中有7例可识别出脑回简化。这些图像可作为向临床医生和其他相关方传达MRI检查结果的视觉辅助工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/200e/5009174/847d87c56246/247_2016_3638_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/200e/5009174/1957646f754f/247_2016_3638_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/200e/5009174/bf0d9a5748e1/247_2016_3638_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/200e/5009174/f6f1fc8a4b87/247_2016_3638_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/200e/5009174/847d87c56246/247_2016_3638_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/200e/5009174/1957646f754f/247_2016_3638_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/200e/5009174/bf0d9a5748e1/247_2016_3638_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/200e/5009174/f6f1fc8a4b87/247_2016_3638_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/200e/5009174/847d87c56246/247_2016_3638_Fig4_HTML.jpg

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