Trenerry M R, Westerveld M, Meador K J
Division of Psychology, Mayo Clinic, Rochester, MN 55905, USA.
Magn Reson Imaging. 1995;13(8):1125-32. doi: 10.1016/0730-725x(95)02022-l.
A review is provided of recent findings on relationships between neurocognitive test data and magnetic resonance imaging (MRI)-determined hippocampal volumes in nonlesional temporal lobectomy patients. The difference between the right and left hippocampal volumes is correlated with postoperative verbal memory in left temporal lobectomy patients who do not have lesional pathology. MRI hippocampal volume data are not associated with measures of executive functioning or naming. Sex differences have been found for verbal memory outcome as women have better verbal memory following left temporal lobectomy. Sex differences have also been found in the relationships between verbal and visual memory, and hippocampal volume data. The systematic combination of MRI-acquired morphological data and neuropsychological test data may further our understanding of neurocognitive function, and provide clinically useful data for counseling epilepsy surgery patients. The current data are promising with regard to prediction of memory outcome following temporal lobectomy, but they do not yet allow for prediction of specific individual patient outcomes. Rather, the currently available data support counseling patients based on the memory outcome of others with similar characteristics.
本文综述了非病变性颞叶切除术患者神经认知测试数据与磁共振成像（MRI）测定的海马体积之间关系的最新研究结果。在没有病变病理的左侧颞叶切除术患者中，左右海马体积的差异与术后言语记忆相关。MRI海马体积数据与执行功能或命名测量无关。在言语记忆结果方面发现了性别差异，因为女性在左侧颞叶切除术后有更好的言语记忆。在言语和视觉记忆以及海马体积数据之间的关系中也发现了性别差异。MRI获取的形态学数据与神经心理学测试数据的系统结合可能会增进我们对神经认知功能的理解，并为癫痫手术患者的咨询提供临床有用的数据。目前的数据在预测颞叶切除术后的记忆结果方面很有前景，但它们还不能预测特定个体患者的结果。相反，目前可用的数据支持根据具有相似特征的其他人的记忆结果为患者提供咨询。
