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[患者视网膜激光凝固术中的反射测量。自动控制剂量计的研制]

[Reflection measurement during retinal laser coagulation in patients. Development of an automatically controlled dosimeter].

作者信息

Inderfurth J, Ferguson R D, Puliafito C A, Frish M B, Birngruber R

机构信息

Wellman Laboratories of Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, USA.

出版信息

Ophthalmologe. 1995 Oct;92(5):717-22.

PMID:8751004
Abstract

PURPOSE

Retinal laser coagulation has limited reproducibility, because every laser exposition is unpredictably affected by pigmentation and media opacities. This can lead to complications. A feedback-controlled dosimeter would make retinal laser treatment a safer, more reproducible and faster procedure.

METHOD

A reflectometer was developed that allows monitoring of the reflection of laser light during standard photocoagulation. Hundreds of coagulations in rabbit eyes and about 12,000 coagulations in patients undergoing routine laser treatment were recorded.

RESULTS

The results of the first reflectance measurements in humans are presented along with extensive animal studies. A typical reflectance history was found for different lesion intensities. The degree of retinal whitening correlates with reflectance characteristics. These characteristics allow an early prediction of lesion intensity. Motion during laser exposure affects each coagulation in a fashion similar to spot size and exposure time.

CONCLUSION

Reflectometry is the currently most effective means of monitoring lesion development. An automatic dosimeter for retinal photocoagulation seems feasible.

摘要

目的

视网膜激光凝固术的可重复性有限,因为每次激光照射都会受到色素沉着和介质混浊的不可预测影响。这可能导致并发症。反馈控制剂量计将使视网膜激光治疗成为更安全、更具可重复性且更快的手术。

方法

开发了一种反射计,可在标准光凝过程中监测激光的反射。记录了兔眼中数百次凝固以及接受常规激光治疗患者的约12000次凝固。

结果

展示了人类首次反射率测量结果以及广泛的动物研究。发现了不同病变强度的典型反射率变化过程。视网膜变白程度与反射率特征相关。这些特征允许早期预测病变强度。激光照射期间的运动对每次凝固的影响方式类似于光斑大小和照射时间。

结论

反射测量法是目前监测病变发展最有效的手段。用于视网膜光凝的自动剂量计似乎是可行的。

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