Miyasaki H, Hasegawa O, Arita T, Komiyama A, Aoba S
Department of Neurology, Yokohama City, University School of Medicine, Japan.
No To Shinkei. 1996 Jul;48(7):649-52.
Proximal conduction time (PCT) of the median nerve was calculated from the data obtained by conventional motor conduction studies in 272 diabetics and in 35 age-matched healthy controls. M-latency and F-latency obtained by stimulation at the wrist (Mw and Fw, respectively) and M-latency at the Erb's point (Me) were used to calculate PCT (Fw + Mw - 2Me), which represents turnaround time between Erb's point and anterior horn cell. Each indices were corrected using the standard patient's height of 160cm. Severity of diabetic neuropathy was shown by the polyneuropathy index (PNI), which was calculated from 12 indices derived from the motor nerve conduction studies on 4 nerves of the right arm and leg. Significant differences were found in Mw, Fw and Me between diabetics and controls (p < 0.01), although the results of PCT were similar between them. In diabetics Mw (r = -0.55), Fw (r = -0.56) and Me (r = -0.60) had a significant negative correlation with PNI, but the correlation between PCT and PNI was relatively low (r = -0.22). Using the proximal conduction time calculated readily from conventional motor nerve conduction studies, delay in the proximal conduction was shown to be smaller than that in the distal conduction in diabetic polyneuropathy.
通过常规运动传导研究获取的数据，计算了272例糖尿病患者及35例年龄匹配的健康对照者正中神经的近端传导时间（PCT）。利用在腕部刺激获得的M波潜伏期和F波潜伏期（分别为Mw和Fw）以及在Erb点的M波潜伏期（Me）来计算PCT（Fw + Mw - 2Me），其代表了从Erb点到前角细胞的折返时间。每个指标均根据标准患者身高160cm进行校正。糖尿病性神经病变的严重程度通过多神经病变指数（PNI）表示，该指数由右臂和腿部4条神经的运动神经传导研究得出的12个指标计算得出。糖尿病患者与对照组之间在Mw、Fw和Me方面存在显著差异（p < 0.01），尽管他们的PCT结果相似。在糖尿病患者中，Mw（r = -0.55）、Fw（r = -0.56）和Me（r = -0.60）与PNI呈显著负相关，但PCT与PNI之间的相关性相对较低（r = -0.22）。利用从常规运动神经传导研究中容易计算出的近端传导时间，结果显示糖尿病性多发性神经病变中近端传导延迟小于远端传导延迟。
