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[对接受联合治疗的内源性抑郁症难治性患者血小板5-羟色胺转运复合体的临床生物学研究]

[A clinico-biological study of the thrombocyte serotonin-transport complex in therapeutically resistant patients with endogenous depression undergoing combined treatment].

作者信息

Brusov O S, Panteleeva G P, Bondar' V V, Dikaia V I, Faktor M I, Zlobina G P, Pavlova O A, Abrosimov N V, Lideman R R

出版信息

Vestn Ross Akad Med Nauk. 1996(4):29-32.

PMID:8754076
Abstract

The platelet parameters of the functional status of the serotonin-reuptake complex were studied in drug-resistant depressive patients given various regimens of complex therapy or selective serotonin re-uptake inhibitors (fluvoxamine and fluoxetine). The most persistent and marked clinical effect was seen in electroconvulsive therapy and it was due to the normalization of the serotonin-reuptake system.

摘要

在接受各种综合治疗方案或选择性5-羟色胺再摄取抑制剂（氟伏沙明和氟西汀）治疗的耐药性抑郁症患者中，研究了5-羟色胺再摄取复合体功能状态的血小板参数。电休克治疗显示出最持久和显著的临床效果，这是由于5-羟色胺再摄取系统恢复正常所致。

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